Open Close
General Information
Symbol
Dmel\Rcc1VV179
Species
D. melanogaster
Name
FlyBase ID
FBal0157263
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

C5931060T

Reported nucleotide change:

C1714T

Amino acid change:

P388L | Rcc1-PA; P388L | Rcc1-PB; P388L | Rcc1-PC

Reported amino acid change:

P?L

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Nucleotide substitution: C1714T. Amino acid replacement: P?L. The mutation is near the end of the fourth RCC repeat.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous mutant embryos exhibit an approximately 50% reduction of EL neurons with 3-5 ELs developing per abdominal hemisegment. These mutant embryos also exhibit morphological defects in the lateral CNS as the lateral margin of mutant nerve cords appear rough and scalloped relative to wild-type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Bj1VV179
Rcc1VV179
Name Synonyms
Secondary FlyBase IDs
    References (1)