FlyBase Allele Report: Dmel\Fadd[f02804]

General Information

Symbol

Dmel\Fadd^f02804

Species

D. melanogaster

Name

FlyBase ID

FBal0157270

Feature type

allele

Associated gene

Dmel\Fadd

Associated Insertion(s)

Carried in Construct

Also Known As

dfadd^f02804

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Naitza et al., 2002)

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal immune response

(Naitza et al., 2002)

Phenotype Manifest In

spermatid

(Huh et al., 2004)

Detailed Description

Statement

Reference

Homozygous flies are more resistant to Cricket Paralysis virus infection (after being injected with the virus) than control flies.

(Costa et al., 2009)

Defects are seen in the movement of investment cones in mutant spermatid, which normally move tailwards in a co-ordinated fashion. Almost all cysts from mutant testes display defects in individualisation. In other cysts individually occurs apparently normal.

(Huh et al., 2004)

Fadd^f02804 homozygous flies show a severe susceptibility to E.coli infection (all flies die within 3 days of infection) and close to wild type resistance to Gram-positive Streptococcus faecalis.

(Naitza et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Fadd^f02804 is a non-enhancer of abnormal neuroanatomy | adult stage | progressive | conditional phenotype of norpA^EE5

(Chinchore et al., 2012)

NOT Suppressor of

Statement

Reference

Fadd^f02804 is a non-suppressor of abnormal neuroanatomy | adult stage | progressive | conditional phenotype of norpA^EE5

(Chinchore et al., 2012)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Fadd^f02804 is a non-enhancer of retina | progressive | conditional phenotype of norpA^EE5

(Chinchore et al., 2012)

NOT Suppressor of

Statement

Reference

Fadd^f02804 is a non-suppressor of retina | progressive | conditional phenotype of norpA^EE5

(Chinchore et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

BG4^f02804

Fadd^f02804

dFADD^f02804

(Costa et al., 2009, Naitza et al., 2002)

dfadd^f02804

(Chinchore et al., 2012)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

Open Close