FB2026_03 , released September 17, 2026
Allele: Dmel\MotorBG00376
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General Information
Symbol
Dmel\MotorBG00376
Species
D. melanogaster
Name
FlyBase ID
FBal0157315
Feature type
allele
Associated gene
Dmel\Motor
Associated Insertion(s)
P{GT1}MotorBG00376
Carried in Construct
Also Known As
BG00376
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GT1}MotorBG00376
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GT1}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        CG3638BG00376 homozygous males have significantly increased levels of aggression. (P < 0.0001; Male aggression index = 18.45). The mushroom body alpha and beta-lobes in these animals are significantly wider, relative to overall brain size, than in wild-type (P <0.0001 for alpha-lobes, P < 0.05 for beta-lobes). However, precise excision of P{GT1}CG3638BG00376 does not consistently revert the increased aggression phenotype.

        (Edwards et al., 2009)

        Heterozygous males and females show a significant decrease in starvation resistance compared to controls.

        (Harbison et al., 2004)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Precise excision of P{GT1}CG3638BG00376 does not consistently revert the increased aggression phenotype seen in CG3638BG00376 homozygous animals.

        (Edwards et al., 2009)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (4)
        Reported As
        Symbol Synonym
        BG00376
        (Harbison et al., 2004)
        BG00376BG00376
        (Edwards et al., 2009)
        CG3638BG00376
        MotorBG00376
        Name Synonyms
        Secondary FlyBase IDs
          References (2)