FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\14-3-3εEP3578
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General Information
Symbol
Dmel\14-3-3εEP3578
Species
D. melanogaster
Name
FlyBase ID
FBal0157548
Feature type
allele
Associated gene
Dmel\14-3-3ε
Associated Insertion(s)
P{EP}14-3-3εEP3578
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(FlyBase, 1996-)
Progenitor genotype
Associated Insertion(s)
P{EP}14-3-3εEP3578
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of 14-3-3εEP3578 driven by Scer\GAL4[GMR.PF] in the retina does not affect eye structure.

      Overexpression of 14-3-3εEP3578 by either Scer\GAL4Switch1.106 or Scer\GAL4bun-Switch1.32 has no apparent effect on lifespan.

      (Nielsen et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      14-3-3εEP3578, Scer\GAL4GMR.PF is a suppressor of visible phenotype of Scer\GAL4GMR.PF, foxoUAS.Tag:FLAG

      (Nielsen et al., 2008)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      14-3-3εEP3578, Scer\GAL4GMR.PF is a suppressor of eye phenotype of Scer\GAL4GMR.PF, foxoUAS.Tag:FLAG

      (Nielsen et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The eye phenotype resulting from the overexpression of foxoScer\UAS.T:Zzzz\FLAG driven by Scer\GAL4GMR.PF is suppressed by 14-3-3εEP3578 overexpression.

      (Nielsen et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      14-3-3EP357
      (Nielsen et al., 2008)
      14-3-3εEP3578
      (Nielsen et al., 2008)
      14-3-3οEP3578
      (Nielsen et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)