FB2026_02 , released June 18, 2026
Allele: Dmel\eca2
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General Information
Symbol
Dmel\eca2
Species
D. melanogaster
Name
FlyBase ID
FBal0159275
Feature type
allele
Associated gene
Dmel\eca
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Bartoszewski et al., 2004)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    300 bp deletion in the eca gene.

    (Bartoszewski et al., 2004)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    delins
    3R:9,685,089..9,685,357 [-]
    Comment:

    269 bases deleted and replaced with an A nucleotide.

    Inserted_sequence:

    A

    (Bartoszewski et al., 2004)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Embryos derived from homozygous eca2 germ-line clones exhibit a weak ventralised phenotype. Homozygotes show reduced survival, eclosing at a rate between 0.1 to 20% of the expected number. Homozygous or hemizygous males show reduced fertility and females lay no eggs, although many developed late oocytes are present in their ovaries which appear morphologically normal. eca2/Df(3R)GB104 animals raised at 19oC exhibit some thickening of the wing veins.

        (Bartoszewski et al., 2004)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        NOT Enhancer of
        Statement
        Reference

        eca2 is a non-enhancer of embryonic/first instar larval cuticle | dorsal | germline clone phenotype of put10460

        (Bartoszewski et al., 2004)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        eca2
        Name Synonyms
        Secondary FlyBase IDs
          References (1)