FlyBase Allele Report: Dmel\Gαi[EY10355]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Gαi^EY10355

General Information

Symbol

Dmel\Gαi^EY10355

Species

D. melanogaster

Name

FlyBase ID

FBal0160445

Feature type

allele

Associated gene

Associated Insertion(s)

P{EPgy2}Gαi^EY10355

Carried in Construct

Key Links

Genomic Maps

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EPgy2}Gαi^EY10355

Cytology

Description

Allele components

Component

Use(s)

Inserted element

misexpression element

Regulatory region(s)

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:6,976,221..6,976,221 [-]

(Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates Huntington's disease

modeled by Hsap\HTT^{128Q.1-336.UAS}

(Kaltenbach et al., 2007)

ameliorates Huntington's disease

modeled by Hsap\HTT^{128Q.1-336.UAS}

(Shirasaki et al., 2012)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

(Gene Disruption Project members, 2001-)

(Gene Disruption Project members, 2001-)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Gαi^EY10355, Scer\GAL4^GMR.PU is an enhancer of visible phenotype of Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Suppressor of

Statement

Reference

Gαi^EY10355, Scer\GAL4^elav.PU is a suppressor of abnormal locomotor behavior | adult stage | progressive phenotype of Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU

(Shirasaki et al., 2012)

Phenotype Manifest In

Enhancer of

Statement

Reference

Gαi^EY10355, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

EY10355

(Kaltenbach et al., 2007)

G-iα65A^EY10355

Giα65A^EY10355

(Shirasaki et al., 2012)

Gαi^EY10355

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections