FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Sap130EY12079
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General Information
Symbol
Dmel\Sap130EY12079
Species
D. melanogaster
Name
FlyBase ID
FBal0162626
Feature type
allele
Associated gene
Dmel\Sap130
Associated Insertion(s)
P{EPgy2}Sap130EY12079
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Cao et al., 2008)
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}Sap130EY12079
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  Alzheimer's disease
      modeled by Hsap\APPAβ42.GMR.Tag:SS(rPENK)
      (Cao et al., 2008)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      CG11006EY12079 fails to complement a quantitative trait locus (QTL) for aggressive behaviour; the CG11006EY12079/QTL genotype shows higher levels of aggression than the CG11006EY12079/wild-type genotype.

      (Edwards and Mackay, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      CG11006[+]/Sap130EY12079 is an enhancer of eye phenotype of Hsap\APPAβ42.GMR.Tag:SS(rPENK)

      (Cao et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG11006EY12079
      (Edwards and Mackay, 2009)
      SAP130EY12079
      (Cao et al., 2008)
      Sap130EY12079
      Name Synonyms
      Secondary FlyBase IDs
        References (3)