Homozygous adult escapers are female sterile.

The synaptonemal complex assembles normally in the ovaries of Cap-G^K3/Df(2R)vg56 females. However, disassembly of the synaptonemal complex is delayed in these females.

The condensed chromosomes normally present in the polar body rosette structure of early embryos have aberrant morphology in embryos derived from Cap-G^K3 females; the chromosomes are pulverised.

Only 23% of the expected number of adult homozygous males and 64% of the expected number of homozygous females eclose. Cap-G^K3/Df(2R)vg56 mutant postblastoderm embryos show abnormal chromosome condensation during prometaphase and failure of sister chromatid separation during anaphase. Defects in mitotic figures are seen in Cap-G^K3/Df(2R)vg56 third larval instar brains. Many metaphase figures have fewer number of chromosomes than in wild type, while others are polyploid. In these metaphase figures, the centromeres appear to be dissociated, while the sister chromatids appear to be associated along the length of the arms. Anaphase figures with sister chromatid bridging and lagging chromosomes are seen. The DAPI-bright region of the heterochromatin is longer in mutant embryos than in the wild type. Adult Cap-G^K3/Df(2R)vg56 survivors have wing notches and rough eyes.