FlyBase Allele Report: Dmel\Alh[L.UAS]

General Information

Symbol

Dmel\Alh^L.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0176408

Feature type

allele

Associated gene

Dmel\Alh

Associated Insertion(s)

Carried in Construct

P{UAS-Alh.L}

Key Links

Transgenic product class

wild_type

(Perrin et al., 2003)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Perrin et al., 2003)

Mutagen

in vitro construct

(Perrin and Dura, 2004, Perrin et al., 2003)

Progenitor genotype

Carried in construct

P{UAS-Alh.L}

Cytology

Description

UAS regulatory sequences drive expression of the Alh L isoform.

(Perrin et al., 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Alh

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

Scer\GAL4^da.G32/Alh^L.UAS is a non-suppressor of lethal phenotype of Mlp84B^y-30

(Perrin and Dura, 2004)

Scer\GAL4^da.G32/Alh^L.UAS is a non-suppressor of lethal phenotype of Mlp84B^y-37

(Perrin and Dura, 2004)

Scer\GAL4^da.G32/Alh^L.UAS is a non-suppressor of abnormal eye color phenotype of w^ph-p.lac+3

(Perrin et al., 2003)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Scer\GAL4^da.G32/Alh^L.UAS is a non-suppressor of pigment cell phenotype of w^ph-p.lac+3

(Perrin et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Eye colour: the eye colour of females carrying w^ph-p.lac+3 is unaffected if they also express Alh^L.Scer\UAS under the control of Scer\GAL4^da.G32. Co-expression of Alh^L.Scer\UAS reduces the effect of expression of Alh::Hsap\MLL^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^da.G32 on the eye colour of females carrying w^ph-p.lac+3.