FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\vihmD1D2.UASp.Tag:polyHis
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General Information
Symbol
Dmel\vihmD1D2.UASp.Tag:polyHis
Species
D. melanogaster
Name
FlyBase ID
FBal0177241
Feature type
allele
Associated gene
Dmel\vih
Associated Insertion(s)
Carried in Construct
P{UASp-vih.mD1D2}
Key Links
Transgenic product class
missense_variant
(Mathe et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Mathe et al., 2004)
Mutagen
in vitro construct
(Mathe et al., 2004)
Progenitor genotype
vihUASp.cMa
(Mathe et al., 2004)
Carried in construct
P{UASp-vih.mD1D2}
Cytology
Description

Mutation in destruction boxes D1 and D2 (amino acid replacements R82A, L85A, R131A and L134A). The protein is tagged with Tag:polyHis.

(Mathe et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
vih
Tagged with
Tag:polyHis
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of vihmD1D2.Scer\UAS.P\T.T:Zzzz\His6 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 in a wild-type or background has no phenotypic effect, although expression of vihmD1D2.Scer\UAS.P\T.T:Zzzz\His6 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 in a vih+/vih- background results in female sterility.

      (Mathe et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      vihmD1D2.Scer\UAS.P\T.T:Zzzz\His6
      vihmD1D2.UASp.Tag:polyHis
      Name Synonyms
      Secondary FlyBase IDs
        References (1)