FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\slohs.B52H
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General Information
Symbol
Dmel\slohs.B52H
Species
D. melanogaster
Name
FlyBase ID
FBal0177861
Feature type
allele
Associated gene
Dmel\slo
Associated Insertion(s)
Carried in Construct
P{hs-slo.B52H}
Also Known As
B52H
Key Links
Transgenic product class
cDNA
(Ghezzi et al., 2004)
wild_type
(Ghezzi et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Ghezzi et al., 2004)
wild_type
(Ghezzi et al., 2004)
Mutagen
in vitro construct
(Ghezzi et al., 2004)
Progenitor genotype
Carried in construct
P{hs-slo.B52H}
Cytology
Description

An inducible hsp70 promoter drives expression of a slo cDNA.

(Ghezzi et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
slo
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  alcohol use disorder
      CEA
      (Ghezzi et al., 2004)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant animals exposed to heat-shock treatment and exposed to benzyl alcohol exhibit an increased resistance to benzyl alcohol when exposed 24 hours after heat shock.

      (Ghezzi et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      slohs.B52H rescues sloMB11481

      (Jepson et al., 2014)
      Comments

      Expression of slohs.B52H rescues the increase in bouton size at the neuromuscular junction seen in sloMB11481 larvae.

      (Jepson et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      slohs.B52H
      Name Synonyms
      Secondary FlyBase IDs
        References (2)