FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ple+t10.988
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General Information
Symbol
Dmel\ple+t10.988
Species
D. melanogaster
Name
FlyBase ID
FBal0178418
Feature type
allele
Associated gene
Dmel\ple
Associated Insertion(s)
Carried in Construct
P{ple+t10.988}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Friggi-Grelin et al., 2003)
wild_type
(Friggi-Grelin et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Friggi-Grelin et al., 2003)
wild_type
(Friggi-Grelin et al., 2003)
Mutagen
in vitro construct
(Friggi-Grelin et al., 2003)
Progenitor genotype
Carried in construct
P{ple+t10.988}
Cytology
Description

Contains a genomic fragment that extends from -4168bp to +6820bp relative to the ple transcription start site, and includes the entire ple coding region.

(Friggi-Grelin et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
ple
Encoded product / tool
ple
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3L:6,710,594..6,721,888 [-]
Linked to:
PstI-EcoRI restriction fragment
Comment:

Position of restriction fragment on reference sequence inferred by FlyBase curator.

(Friggi-Grelin et al., 2003)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      ple+t10.988 is a suppressor of abnormal flight phenotype of ItprNIG.1063R, Scer\GAL4ple.PF

      (Pathak et al., 2015)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      ple+t10.988 can suppress the flight deficit of Scer\GAL4ple.PF>Itp-r83ANIG.1063R flies.

      (Pathak et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ple+t10.988 rescues pleunspecified

      (Friggi-Grelin et al., 2003)
      Comments

      ple+t10.988 can rescue the embryonic lethality of ple mutants up to the adult stage, but the degree of rescue to adulthood depends markedly on the particular P{ple+t10.988} insertion line used, whereas rescue to the pupal stage is always complete.

      (Friggi-Grelin et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ple+t10.988
      Name Synonyms
      Secondary FlyBase IDs
        References (3)