FB2026_02 , released June 18, 2026
Allele: Dmel\ogreUAS.cCa
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General Information
Symbol
Dmel\ogreUAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Curtin
FlyBase ID
FBal0178595
Feature type
allele
Associated gene
Dmel\ogre
Associated Insertion(s)
Carried in Construct
P{UAS-ogre.C}
Also Known As
UAS-ogre
Key Links
Transgenic product class
wild_type
(Curtin et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Curtin et al., 2002)
Mutagen
in vitro construct
(Curtin et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-ogre.C}
Cytology
Description

UASt regulatory sequences govern expression of ogre.

(Curtin et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
ogre
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ogreUAS.cCa/Scer\GAL4ogre.PC rescues ogre2

      (Curtin et al., 2002)

      ogreUAS.cCa, Scer\GAL4ogre.PC, Scer\GAL4hs.2sev rescues ogre2

      (Curtin et al., 2002)
      Partially rescues

      Scer\GAL4elav-C155/ogreUAS.cCa partially rescues ogre2

      (Curtin et al., 2002)

      ogreUAS.cCa/Scer\GAL4hs.2sev partially rescues ogre2

      (Curtin et al., 2002)

      ogreUAS.cCa/Scer\GAL4ogre.PC partially rescues ogre2

      (Curtin et al., 2002)
      Comments

      Expression of ogreScer\UAS.cCa, via Scer\GAL4elav-C155, which expresses in all neurons from neural birth through adulthood, mediates partial rescue of ogre2 with on-transients that are approximately 57% that of wild-type and off-transients that are approximately 56% that of wild-type. Expression of ogreScer\UAS.cCa, via Scer\GAL4ogre.PC rescues the electroretinogram phenotype of ogre2 mutants, with on-transients that are 61% of wild-type and off-transients that are 72% of wild-type, compared with no transients in ogre2 mutants. Rescue is only consistently observed in light-adapted conditions. Expression of ogreScer\UAS.cCa under the regulation of Scer\GAL4unspecified leads to partial rescue of the ogre2 electroretinogram phenotype with on-transients rescued to approximately 65% and off-transients 58% of wild-type. When expression of ogreScer\UAS.cCa is under the regulation of both Scer\GAL4unspecified and Scer\GAL4ogre.PC, nearly wild-type transients are observed.

      Expression of ogreScer\UAS.cCa, via Scer\GAL4elav-C155, which expresses in all neurons from neural birth through adulthood, mediates partial rescue of ogre2 with on-transients that are approximately 57% that of wild-type and off-transients that are approximately 56% that of wild-type.

      Expression of ogreScer\UAS.cCa, via Scer\GAL4ogre.PC rescues the electroretinogram phenotype of ogre2 mutants, with on-transients that are 61% of wild-type and off-transients that are 72% of wild-type, compared with no transients in ogre2 mutants. Rescue is only consistently observed in light-adapted conditions.

      Expression of ogreScer\UAS.cCa under the regulation of Scer\GAL4hs.2sev leads to partial rescue of the ogre2 electroretinogram phenotype with on-transients rescued to approximately 65% and off-transients 58% of wild-type. When expression of ogreScer\UAS.cCa is under the regulation of both Scer\GAL4hs.2sev and Scer\GAL4ogre.PC, nearly wild-type transients are observed.

      (Curtin et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ogreScer\UAS.cCa
      ogreUAS.cCa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Curtin
      (Curtin et al., 2002)
      Secondary FlyBase IDs
        References (2)