FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mysb43
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General Information
Symbol
Dmel\mysb43
Species
D. melanogaster
Name
FlyBase ID
FBal0178737
Feature type
allele
Associated gene
Dmel\mys
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Jannuzi et al., 2004)
Progenitor genotype
Cytology
Description

Amino acid replacement: G347S.

(Jannuzi et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:8,067,284..8,067,284 [+]
Nucleotide change:

G8067284A

Amino acid change:

G347S | mys-PA; G347S | mys-PB; G347S | mys-PC; G347S | mys-PD

Reported amino acid change:

G347S

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change. Same mutation as mysb42.

(Jannuzi et al., 2004)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Weak allele.

      (Jannuzi et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      mys[+]/mysb43 is an enhancer of visible | female phenotype of FakUAS.Tag:HA, Scer\GAL4en-e16E

      (Grabbe et al., 2004)
      Other
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      mys[+]/mysb43 is an enhancer of wing | female phenotype of FakUAS.Tag:HA, Scer\GAL4en-e16E

      (Grabbe et al., 2004)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The penetrance of the wing blistering phenotype seen in females expressing Fak56DScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4en-e16E at 25oC is increased from 28% to 40% if they are carrying mysb43/+. Males expressing Fak56DScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4en-e16E at 25oC and hemizygous for mysb43 show 21% wing blistering (compared to 0% wing blistering in a mys+ background).

      (Grabbe et al., 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a mutation that permits the survival of an F1 male.

      (Jannuzi et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      mysb43
      Name Synonyms
      Secondary FlyBase IDs
        References (2)