FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mib14
Open Close
General Information
Symbol
Dmel\mib14
Species
D. melanogaster
Name
FlyBase ID
FBal0178895
Feature type
allele
Associated gene
Dmel\mib1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - genetic evidence

    (Le Borgne et al., 2005)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: V457M.

    (Le Borgne et al., 2005)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3L:16,009,163..16,009,163 [-]
    Nucleotide change:

    G16009163A

    Amino acid change:

    V457M | mib1-PA; V346M | mib1-PB

    Reported amino acid change:

    V457M

    Comment:

    Site of nucleic acid difference inferred by FlyBase based on reported amino acid change

    (Le Borgne et al., 2005)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        11% of mib13/mib14 flies show a wing nicking phenotype.

        (Hamel et al., 2010)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressed by
        Statement
        Reference

        mib14/mib13 has visible phenotype, suppressible by α4GT1GS2078/Scer\GAL4Ser.PGF

        (Hamel et al., 2010)
        Phenotype Manifest In
        Suppressed by
        Statement
        Reference

        mib14/mib13 has wing phenotype, suppressible by α4GT1GS2078/Scer\GAL4Ser.PGF

        (Hamel et al., 2010)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The penetrance of the wing nicking phenotype seen in mib13/mib14 flies is decreased to 1% if they are also expressing α4GT1GS2078 under the control of Scer\GAL4Ser.PGF post-embryonically (animals are transferred to 28[o]C after embryogenesis to inactivate Scer\GAL80ts.αTub84B which is present in the stock).

        (Hamel et al., 2010)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        mib1EY09780

        (Le Borgne et al., 2005)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        l(3)72CdaI5
        (Le Borgne et al., 2005)
        mib14
        (Hamel et al., 2010)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)