FlyBase Allele Report: Dmel\α4GT1[GS2078]

General Information

Symbol

Dmel\α4GT1^GS2078

Species

D. melanogaster

Name

FlyBase ID

FBal0246148

Feature type

allele

Associated gene

Dmel\α4GT1

Associated Insertion(s)

P{GSV1}α4GT1^GS2078

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GSV1}α4GT1^GS2078

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GSV1}

misexpression element

Regulatory region(s)

UASt

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:3,023,225..3,023,225

(Hamel et al., 2010)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

α4GT1^GS2078, Scer\GAL4^pnr-MD237 is a suppressor of visible phenotype of Scer\GAL4^pnr-MD237, Tom^UAS.cLa

(Hamel et al., 2010)

α4GT1^GS2078, Scer\GAL4^Ser.PGF is a suppressor of visible phenotype of Scer\GAL4^Ser.PGF, mib1^C1205S.UAS

(Hamel et al., 2010)

α4GT1^GS2078/Scer\GAL4^Ser.PGF is a suppressor of visible phenotype of mib1⁴/mib1³

(Hamel et al., 2010)

α4GT1^GS2078, Scer\GAL4^Ser.PGF is a suppressor of visible phenotype of Scer\GAL4^Ser.PGF, mib1^GD11786

(Hamel et al., 2010)

α4GT1^GS2078, Scer\GAL4^pnr-MD237 is a suppressor of visible phenotype of Scer\GAL4^pnr-MD237, neur^NIG.11988R

(Hamel et al., 2010)

NOT Suppressor of

Statement

Reference

α4GT1^GS2078/Scer\GAL4^Ser.PGF is a non-suppressor of visible phenotype of mib1³/Df(3L)mib1²

(Hamel et al., 2010)

Phenotype Manifest In

Suppressor of

Statement

Reference

α4GT1^GS2078, Scer\GAL4^pnr-MD237 is a suppressor of chaeta | increased number phenotype of Scer\GAL4^pnr-MD237, Tom^UAS.cLa

(Hamel et al., 2010)

α4GT1^GS2078, Scer\GAL4^Ser.PGF is a suppressor of wing phenotype of Scer\GAL4^Ser.PGF, mib1^C1205S.UAS

(Hamel et al., 2010)

α4GT1^GS2078/Scer\GAL4^Ser.PGF is a suppressor of wing phenotype of mib1⁴/mib1³

(Hamel et al., 2010)

α4GT1^GS2078, Scer\GAL4^Ser.PGF is a suppressor of wing phenotype of Scer\GAL4^Ser.PGF, mib1^GD11786

(Hamel et al., 2010)

α4GT1^GS2078, Scer\GAL4^pnr-MD237 is a suppressor of chaeta | increased number phenotype of Scer\GAL4^pnr-MD237, neur^NIG.11988R

(Hamel et al., 2010)

NOT Suppressor of

Statement

Reference

α4GT1^GS2078/Scer\GAL4^Ser.PGF is a non-suppressor of wing phenotype of mib1³/Df(3L)mib1²

(Hamel et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of α4GT1^GS2078 results in strong suppression of the wing phenotype caused by expression of mib1^GD11786 under the control of Scer\GAL4^Ser.PGF post-embryonically (animals are transferred to 28[o]C after embryogenesis to inactivate Scer\GAL80^ts.αTub84B which is present in the stock).

Co-expression of α4GT1^GS2078 results in strong suppression of the wing phenotypes caused by expression of mib1^{C1205S.Scer\UAS} under the control of Scer\GAL4^Ser.PGF post-embryonically (animals are transferred to 28[o]C after embryogenesis to inactivate Scer\GAL80^ts.αTub84B which is present in the stock).

he penetrance of the wing nicking phenotype seen in mib1³/mib1⁴ flies is decreased to 1% if they are also expressing α4GT1^GS2078 under the control of Scer\GAL4^Ser.PGF post-embryonically (animals are transferred to 28[o]C after embryogenesis to inactivate Scer\GAL80^ts.αTub84B which is present in the stock).

The wing phenotype of Df(3L)mib1²/mib1³ flies is not modified by expression of α4GT1^GS2078 under the control of Scer\GAL4^Ser.PGF post-embryonically (animals are transferred to 28[o]C after embryogenesis to inactivate Scer\GAL80^ts.αTub84B which is present in the stock).

The excess bristles phenotype caused by expression of either Tom^Scer\UAS.cLa or neur^NIG.11988R under the control of Scer\GAL4^pnr-MD237 post-embryonically (animals are transferred to 28[o]C after embryogenesis to inactivate Scer\GAL80^ts.αTub84B which is present in the stock) is suppressed by co-expression of α4GT1^GS2078.

(Hamel et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

200250

y¹ w^67c23; P{GSV1}α4GT1^GS2078/SM1

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

α4GT1^GS2078

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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