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General Information
Symbol
Dmel\easUAS.cPa
Species
D. melanogaster
Name
FlyBase ID
FBal0180036
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-eas+
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS sequences drive expression of eas.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of easScer\UAS.cPa under the simultaneous control of both Scer\GAL4tin.cBa and Scer\GAL4Scer\UAS.cHa improves heart performance under stress compared to control flies.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

Expression of easScer\UAS.cPa under the control of Scer\GAL4HCH.Hand significantly normalises the heart period of eas2 mutant adults, mainly by restoring the diastolic interval to normal levels. In addition, the cardiac chamber appears normal in size in the rescued animals.

Expression of easScer\UAS.cPa under the control of Scer\GAL4HCH.Hand rescues the stress-induced heart failure rates of eas2 adult hearts to normal levels.

The majority of flies have brains of wild-type appearance when easScer\UAS.cPa is expressed under the control of Scer\GAL4OK107 in a easalaE13 background.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
easScer\UAS.cPa
easUAS.cPa
Name Synonyms
Secondary FlyBase IDs
    References (4)