FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\diaZ4053
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General Information
Symbol
Dmel\diaZ4053
Species
D. melanogaster
Name
FlyBase ID
FBal0180214
Feature type
allele
Associated gene
Dmel\dia
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Giansanti et al., 2004)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      Nebenkern

      (Giansanti et al., 2004)

      spermatid & nucleus | supernumerary

      (Giansanti et al., 2004)
      Detailed Description
      Statement
      Reference

      A large proportion of diaZ4053 mutant spermatids have one large nebenkern with two nuclei of normal size, indicating failure of cytokinesis in one of the meiotic divisions. A smaller amount of spermatids have four nuclei and a large nebenkern, indicating a cytokinetic failure in both meiotic divisions. Occasionally spermatids are seen (<1% of cases) with three nuclei, which may be due to failure of cytokinesis in the first meiotic division, followed by budding off of only one daughter cell in the second meiotic division. The same phenotype is seen in diaZ4053/Df(2L)TW84 spermatids, except a greater proportion (>6%) have three nuclei.

      (Giansanti et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      diaZ4053
      Name Synonyms
      Secondary FlyBase IDs
        References (1)