FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\apf08090
Open Close
General Information
Symbol
Dmel\apf08090
Species
D. melanogaster
Name
FlyBase ID
FBal0180968
Feature type
allele
Associated gene
Dmel\ap
Associated Insertion(s)
PBac{WH}apf08090
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Gene Disruption Project members and Exelixis, 2005)
Progenitor genotype
Associated Insertion(s)
PBac{WH}apf08090
Cytology
Description
Allele components
Component
Use(s)
Inserted element
PBac{WH}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Wing defects are seen in aploxP.MCP-PRE.MM/apf08090 mutant flies, but they are significantly less severe than those seen in aploxP.MCP-PRE.MM homozygotes.

      Wing defects are seen in Df(2R)DG-Mcp/apf08090 mutant flies, but they are less severe than those seen in Df(2R)DG-Mcp homozygotes.

      Mild wing defects are seen in Df(2R)DG/apf08090 mutant flies, but they are less severe than those seen in Df(2R)DG homozygotes.

      (Gohl et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The lethality of this chromosome cannot be reverted by excision of the PBac{WH}, indicating that it is associated with a second site lethal. Rare homozygous revertant escapers as well as frequent hemizygous revertants have normal wings, suggesting that the PBac{WH} insert is responsible for the strong wing phenotype in hemizygous apf08090 flies.

      (Bieli et al., 2015)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      apf08090
      (Bieli et al., 2015, Gohl et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)