FlyBase Allele Report: Dmel\Uev1A[DG14805]

General Information

Symbol

Dmel\Uev1A^DG14805

Species

D. melanogaster

Name

FlyBase ID

FBal0181098

Feature type

allele

Associated gene

Dmel\Uev1A

Associated Insertion(s)

P{wHy}Uev1A^DG14805

Carried in Construct

Also Known As

dUev1A^DG14805

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gelbart, 2008.3.31)

Progenitor genotype

Associated Insertion(s)

P{wHy}Uev1A^DG14805

Cytology

Description

P{wHy}Uev1A^DG14805 is inserted 6 amino acid residues after the ATG translation start site.

(Ma et al., 2013)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:5,366,138..5,366,138 [+]

(Ma et al., 2013, Gelbart, 2008.3.31, Myrick et al., 2005.5.16)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage (with Df(3L)Exel6104)

(Ma et al., 2013)

lethal - all die before end of pupal stage (with Df(3L)Exel6105)

(Ma et al., 2013)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Uev1A^DG14805 is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, cindr^{RNAi.PC.PD.UAS}

(Ketosugbo et al., 2017)

Suppressor of

Statement

Reference

Uev1A[+]/Uev1A^DG14805 is a suppressor of increased cell growth rate phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

Uev1A[+]/Uev1A^DG14805 is a suppressor of abnormal neuroanatomy phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

Uev1A[+]/Uev1A^DG14805 is a suppressor of increased body size phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

Uev1A[+]/Uev1A^DG14805 is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

Uev1A[+]/Uev1A^DG14805 is a suppressor | partially of increased cell death phenotype of Scer\GAL4^FRT.Act5C, egr^UAS.cIa

(Ma et al., 2013)

Df(3L)Exel6104/Uev1A^DG14805 is a suppressor of increased cell death phenotype of Scer\GAL4^FRT.Act5C, egr^UAS.cIa

(Ma et al., 2013)

Phenotype Manifest In

Enhancer of

Statement

Reference

Uev1A^DG14805 is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, cindr^{RNAi.PC.PD.UAS}

(Ketosugbo et al., 2017)

Suppressor of

Statement

Reference

Uev1A[+]/Uev1A^DG14805 is a suppressor of larval ventral nerve cord phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

Uev1A[+]/Uev1A^DG14805 is a suppressor of larva phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

Uev1A[+]/Uev1A^DG14805 is a suppressor | partially of eye phenotype of Scer\GAL4^FRT.Act5C, egr^UAS.cIa

(Ma et al., 2013)

Df(3L)Exel6104/Uev1A^DG14805 is a suppressor of eye phenotype of Scer\GAL4^FRT.Act5C, egr^UAS.cIa

(Ma et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

A Uev1A^DG14805 heterozygous mutant background dramatically suppresses the Ras85D^V12.Scer\UAS/l(2)gl⁴ mutant tumour growth and invasion, and rescues animals to pupal stage.

(Ma et al., 2013)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

20440

y¹ w^67c23; P{wHy}Uev1A^DG14805/TM3, Sb¹ Ser¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Uev1A^DG14805

Uev1a^DG14805

(Ketosugbo et al., 2017)

dUev1A^DG14805

(Bai et al., 2020, Ma et al., 2013)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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