FB2026_03 , released September 17, 2026
Allele: Dmel\Top3αhs.PP
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General Information
Symbol
Dmel\Top3αhs.PP
Species
D. melanogaster
Name
heat shock construct of Plank
FlyBase ID
FBal0181192
Feature type
allele
Associated gene
Dmel\Top3α
Associated Insertion(s)
Carried in Construct
P{hs-Top3α.P}
Key Links
Transgenic product class
wild_type
(Plank et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Plank et al., 2005)
Mutagen
in vitro construct
(Plank et al., 2005)
Progenitor genotype
Carried in construct
P{hs-Top3α.P}
Cytology
Description

An Hsp70 promoter drives expression of the Top3α coding sequence fused to the 3' untranslated region of Act5C.

(Plank et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Top3α
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Top3αhs.PP partially rescues Top3α191

      (Plank et al., 2005)
      Comments

      The lethality of Top3α191 homozygotes is rescued with 40-50% efficiency by expression of Top3αhs.PP using heat shock.

      (Plank et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Top3αhs.PP
      Name Synonyms
      heat shock construct of Plank
      (Plank et al., 2005)
      Secondary FlyBase IDs
        References (1)