FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CyfipUAS.Tag:Myr(Src64B)
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General Information
Symbol
Dmel\CyfipUAS.Tag:Myr(Src64B)
Species
D. melanogaster
Name
FlyBase ID
FBal0181446
Feature type
allele
Associated gene
Dmel\Cyfip
Associated Insertion(s)
Carried in Construct
P{UAS-Cyfip.Myr}
Key Links
Transgenic product class
wild_type
(Bogdan et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bogdan et al., 2004)
Mutagen
in vitro construct
(Bogdan et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Cyfip.Myr}
Cytology
Description

Expression of the first 88 amino acids of Src64B fused full length Sra-1 is under the control of UAS sequences.

(Bogdan et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Cyfip
Tagged with
Tag:Myr(Src64B)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      microchaeta, with Scer\GAL4sca.PC

      (Bogdan et al., 2004)

      trichogen cell & actin filament & pupa, with Scer\GAL4sca.PC

      (Bogdan et al., 2004)
      Detailed Description
      Statement
      Reference

      Sra-1Scer\UAS.T:Myr1; Scer\GAL4sca.PC flies have short, split microchaetae. During bristle formation in Sra-1Scer\UAS.T:Myr1; Scer\GAL4sca.PC pupae, actin filament formation is initiated in a broader region of the apical cell surface than in wild-type and actin filaments at the cell boundary appear to have a `fuzzier' organization.

      (Bogdan et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Suppressed by
      Statement
      Reference

      CyfipUAS.Tag:Myr(Src64B), Scer\GAL4sca.PC has microchaeta phenotype, suppressible by WASp[+]/WASp3

      (Bogdan et al., 2004)
      NOT suppressed by
      Statement
      Reference

      CyfipUAS.Tag:Myr(Src64B), Scer\GAL4sca.PC has microchaeta phenotype, non-suppressible by Hem[+]/HemJ4-48

      (Bogdan et al., 2004)
      Enhancer of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The short and split microchaetae phenotype of Sra-1Scer\UAS.T:Myr1; Scer\GAL4sca.PC flies is synergistically enhanced by HemScer\UAS.T:Myr1, suppressed by WASp3/+, but is unaffected by HemJ4-48/+.

      (Bogdan et al., 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      CyfipUAS.Tag:Myr(Src64B)
      Sra-1Scer\UAS.T:Myr-Src64B
      Sra-1Scer\UAS.T:Myr1
      Sra-1UAS.Tag:Myr(Src64B)
      SraMyr
      (Bogdan et al., 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)