FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SlbpT120A.T230A.Tag:HA
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General Information
Symbol
Dmel\SlbpT120A.T230A.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0181527
Feature type
allele
Associated gene
Dmel\Slbp
Associated Insertion(s)
Carried in Construct
P{Slbp.T120A.T230A.HA}
Key Links
Transgenic product class
missense_variant
(Lanzotti et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Lanzotti et al., 2004)
Mutagen
in vitro construct
(Lanzotti et al., 2004)
Progenitor genotype
Carried in construct
P{Slbp.T120A.T230A.HA}
Cytology
Description

Amino acid replacement: T120A. Amino acid replacement: T230A. Mutated Slbp tagged with two copies of Tag:HA at the N-terminus. The Slbp fragment corresponds to genomic sequence from the SacII site 612bp upstream of the start codon to the BamHI site 605 bp downstream of the stop codon. Expression is from the endogenous Slbp promoter.

(Lanzotti et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
Slbp
Encoded product / tool
Slbp
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      SlbpT120A.T230A.Tag:HA partially rescues Slbp15/Df(3R)3450

      (Lanzotti et al., 2004)
      Comments

      Two copies of SlbpT120A.T230A.T:Ivir\HA1 partially rescue the viability of Slbp15/Df(3R)3450 mutants, but any rescued females are sterile. One copy of SlbpT120A.T230A.T:Ivir\HA1 is not usually sufficient to achieve rescue; any escapers eclose later then wild type and usually die shortly after eclosion. All rescued males are fertile.

      (Lanzotti et al., 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SlbpT120A.T230A.T:Ivir\HA1
      SlbpT120A.T230A.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)