FB2026_03 , released September 17, 2026
Allele: Mmus\Gpsm2hs.2xTag:FLAG
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General Information
Symbol
Mmus\Gpsm2hs.2xTag:FLAG
Species
M. musculus
Name
FlyBase ID
FBal0182672
Feature type
allele
Associated gene
Mmus\Gpsm2
Associated Insertion(s)
Carried in Construct
P{hs-Mmus\Gpsm2.2xT:Zzzz\FLAG}
Transgenic product class
wild_type
(Yu et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Yu et al., 2003)
Mutagen
in vitro construct
(Yu et al., 2003)
Progenitor genotype
Carried in construct
P{hs-Mmus\Gpsm2.2xT:Zzzz\FLAG}
Cytology
Description

Full-length Mmus\Gpsm2, tagged at the C-terminus with 2 copies of Tag:FLAG, is expressed under the control of a heat shock promoter.

(Yu et al., 2003)
Allele components
Component
Use(s)
Encoded product / tool
Mmus\Gpsm2
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Mmus\Gpsm2hs.2xTag:FLAG is a suppressor of larval RP2 motor neuron | ectopic phenotype of pinsP89

      (Yu et al., 2003)

      Mmus\Gpsm2hs.2xTag:FLAG is a suppressor of RP2sib neuron phenotype of pinsP89

      (Yu et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Ectopic expressed Mmus\Gpsm2hs.2xT:Zzzz\FLAG is able to restore 90o spindle rotation in rapsP89 embryonic neuroblast cells of mitotic domain 9. The introduction of Mmus\Gpsm2hs.2xT:Zzzz\FLAG into rapsP89 mutant embryos allows basal proteins to localize as in wild-type cells. Ectopic expression of Mmus\Gpsm2hs.2xT:Zzzz\FLAG in rapsP89 mutant embryos recues defects in the resolution of alternative neuron sibling cell fate. For example, transformation of RP2 sib neurons to RP2 neurons is largely suppressed.

      (Yu et al., 2003)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mmus\Gpsm2hs.2xT:Zzzz\FLAG
      Mmus\Gpsm2hs.2xTag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)