FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gmd1
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General Information
Symbol
Dmel\Gmd1
Species
D. melanogaster
Name
FlyBase ID
FBal0183409
Feature type
allele
Associated gene
Dmel\Gmd
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Okajima et al., 2005)
Mutagen
P-element activity
(Okajima, 2005)
Progenitor genotype
GmdSH1606
(Okajima, 2005)
Cytology
Description

Imprecise excision of the insertion in Gmd, resulting in a deletion of Gmd nucleotides 65 to 666, as well as all of the first and most of the second intron. This deletion removes sequences encoding amino acids 2 to 202 and results in the introduction of a stop codon after the first two amino acids.

(Okajima, 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:4,976,161..4,976,925 [-]
Comment:

Deletion resulting from the imprecise excision of P{lacW}GmdSH1606 which takes out DNA encoding amino acids 2 to 202 as well all of the first and most of the second intron.

(Okajima, 2005)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous Gmd1 mutants die as larvae and do not exhibit any neurogenic phenotypes. Neurogenic phenotypes are also absent in embryos that are both maternally and zygotically mutant for Gmd1 (generated using females carrying homozygous Gmd1 germline clones). These mutants die at the first instar larval stage.

      (Okajima et al., 2008)

      Mutants can survive to the third larval instar. They show severely decreased growth of the wing disc.

      (Okajima et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Gmd1
      (Kahsai and Cook, 2018, Okajima et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)