FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\C152
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General Information
Symbol
Dmel\C152
Species
D. melanogaster
Name
FlyBase ID
FBal0187948
Feature type
allele
Associated gene
Dmel\C15
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Campbell, 2005)
Progenitor genotype
Cytology
Description

Mutation results in a protein that is truncated before the homeodomain.

(Campbell, 2005)

Amino acid replacement: ?170term.

(Campbell, 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:21,507,148..21,507,148 [+]
Nucleotide change:

C21507148T

Amino acid change:

R203term | C15-PA

Reported amino acid change:

?170term

Comment:

Resulting protein is truncated before the homeodomain. Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Campbell, 2005)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In C152 mutants the aristae are shortened to a vestige. Additionally, the claws, pulvilli and empodium at the tip of the legs are missing and tarsal segments IV and V are reduced compared to wild type. C152 mutants die soon after emerging.

      (Campbell, 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      C152 has arista phenotype, non-enhanceable by alice

      (Campbell, 2005)

      C152 has empodium phenotype, non-enhanceable by alice

      (Campbell, 2005)

      C152 has pulvillus phenotype, non-enhanceable by alice

      (Campbell, 2005)

      C152 has tarsal segment 4 phenotype, non-enhanceable by alice

      (Campbell, 2005)

      C152 has pretarsus phenotype, non-enhanceable by alice

      (Campbell, 2005)

      C152 has unguis phenotype, non-enhanceable by alice

      (Campbell, 2005)
      Enhancer of
      Statement
      Reference

      C152/C15[+] is an enhancer of arista phenotype of alush/al130

      (Campbell, 2005)
      NOT Enhancer of
      Statement
      Reference

      C152 is a non-enhancer of pretarsus phenotype of alice

      (Campbell, 2005)

      C152 is a non-enhancer of unguis phenotype of alice

      (Campbell, 2005)

      C152 is a non-enhancer of arista phenotype of alice

      (Campbell, 2005)

      C152 is a non-enhancer of empodium phenotype of alice

      (Campbell, 2005)

      C152 is a non-enhancer of pulvillus phenotype of alice

      (Campbell, 2005)

      C152 is a non-enhancer of tarsal segment 4 phenotype of alice

      (Campbell, 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The leg and antennae phenotypes of C152; alice double mutants are indistinguishable from either single mutant.

      (Campbell, 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: a mutation that enhances the reduced aristae phenotype in al130/alush mutants.

      (Campbell, 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      C152
      (Bourbon et al., 2022, Mojica-Vázquez et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)