FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Tsp42Ej1
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General Information
Symbol
Dmel\Tsp42Ej1
Species
D. melanogaster
Name
FlyBase ID
FBal0190030
Feature type
allele
Associated gene
Dmel\Tsp42Ej
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Xu et al., 2004)
Progenitor genotype
P{EP}Tsp42EjEP2425
(Xu et al., 2004)
Cytology
Description

Imprecise excision of the P{EP}Tsp42EjEP2425 insertion has deleted a 1.8kb segment that starts upstream of the first exon and removes about half of the Tsp42Ej coding sequence.

(Xu et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The reduction in electroretinogram (ERG) amplitude seen in flies exposed to constant light is partly suppressed by Tsp42Ej1. However, retinal degeneration and rate of loss of the deep pseudopupil in Tsp42Ej1 flies exposed to constant light is the same as that seen in wild-type flies exposed to constant light.

      (Lee and Montell, 2004)

      Mutant animals exhibit light and age dependant retinal degeneration. This degeneration is first evident in the cell bodies.

      (Xu et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Tsp42Ej1 has retina phenotype, suppressible by ninaE7

      (Xu et al., 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Tsp42Ej1 is rescued by Tsp42EjninaE.Tag:MYC

      (Xu et al., 2004)

      Tsp42Ej1 is rescued by Tsp42Ej+t5.0

      (Xu et al., 2004)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tsp42Ej1
      sun1
      (Xu et al., 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)