FB2026_02 , released June 18, 2026
Allele: Dmel\tumUAS.Tag:MYC,YFP
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General Information
Symbol
Dmel\tumUAS.Tag:MYC,YFP
Species
D. melanogaster
Name
FlyBase ID
FBal0190279
Feature type
allele
Associated gene
Dmel\tum
Associated Insertion(s)
Carried in Construct
P{UAS-tum.MYC}
Key Links
Transgenic product class
wild_type
(Goldstein et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Goldstein et al., 2005)
Mutagen
in vitro construct
(Goldstein et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-tum.MYC}
Cytology
Description

UAS regulatory sequences drive expression of tum tagged with Tag:MYC and with YFP.

(Goldstein et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
tum
Tagged with
Tag:MYC
YFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When tumScer\UAS.T:Hsap\MYC,T:Avic\GFP-EYFP is driven by Scer\GAL4OK107 gross mushroom body projection is unaffected.

      (Goldstein et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      Scer\GAL4ey-OK107, pavUASp.mGFP6, tumUAS.Tag:MYC,YFP has mushroom body & axon phenotype

      (Goldstein et al., 2005)

      Scer\GAL4ey-OK107, pavNLS4-7*.UASp.mGFP6, tumUAS.Tag:MYC,YFP has mushroom body & axon phenotype

      (Goldstein et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      When both tumScer\UAS.T:Hsap\MYC,T:Avic\GFP-EYFP and pavScer\UAS.P\T.T:Avic\GFP-m6 are driven in the mushroom body by Scer\GAL4OK107, a high occurrence of axon misguidance is seen, often forming a cluster of axons in a ball like form. When both tumScer\UAS.T:Hsap\MYC,T:Avic\GFP-EYFP and pavNLS4-7*.Scer\UAS.P\T.T:Avic\GFP-m6 are driven in the mushroom body by Scer\GAL4OK107, a high occurrence of axon misguidance is seen. In addition to forming a cluster of axons in a ball like form, axons are seen to bypass their normal path via the peduncle and instead project medially toward the front of the brain just below the normal medial lobe.

      (Goldstein et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      tumUAS.Tag:MYC,YFP/Scer\GAL4ey-OK107 partially rescues tum1

      (Goldstein et al., 2005)
      Comments

      tumScer\UAS.T:Hsap\MYC,T:Avic\GFP-EYFP driven by Scer\GAL4OK107 partially rescues the cytokinetic phenotype seen in tum1 mutant mushroom body clones.

      (Goldstein et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      R. Saint

      (Goldstein et al., 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tumScer\UAS.T:Hsap\MYC,T:Avic\GFP-EYFP
      tumUAS.Tag:MYC,YFP
      Name Synonyms
      Secondary FlyBase IDs
        References (3)