FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gpdh1Δ24-1
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General Information
Symbol
Dmel\Gpdh1Δ24-1
Species
D. melanogaster
Name
FlyBase ID
FBal0190440
Feature type
allele
Associated gene
Dmel\Gpdh1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Gpdh1KG02555
    (Merritt et al., 2006)
    Cytology
    Description

    Imprecise excision of the P{SUPor-P}GpdhKG02555 element, resulting in a 456bp deletion that is replaced by 1.2kb of the P element, including the sequence TTATGTTATTCATCATG.

    (Merritt et al., 2006)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        GpdhΔ24-1 flies possess low triglyceride content compared to control flies that possess full Gpdh activity. GpdhΔ24-1/GpdhΔ10-2 and GpdhΔ9-2/GpdhΔ24-1 flies show a significant reduction in wing-beat frequency compared to controls.

        (Merritt et al., 2006)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        Gpdh1Δ24-1
        GpdhΔ24-1
        GpdhΔ24.1
        (Eanes et al., 2009)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)