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General Information
Symbol
Dmel\dlpMH20
Species
D. melanogaster
Name
FlyBase ID
FBal0190712
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
dlp20
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the P{GSV6}9068 insertion has created a nearly 500bp deletion that removes part of the first exon of the dlp gene, including the first 16bp downstream of the ATG.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In dlpMH20 mutants, the number of ectopic mechanosensory bristles, but not chemosensory bristles, is increased.

Less than 1% of homozygous third instar larvae reach adulthood.

Wings from homozygous escapers are reduced in size compared to controls, with a greater reduction in the intervein area between wing veins 3 and 4 compared to the reduction in overall wing size. Ectopic mechanosensory bristles are present at the anterior wing margin. Homozygous adult escapers also have reduced, rough eyes.

Mutant embryos die with a "denticle lawn" phenotype. A low frequency of animals survive to adulthood. Those adults exhibit supernumerary wing margin bristles on either side of the margin.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
NOT Suppressor of
Statement
Reference

dlpMH20 is a non-suppressor of taste bristle | supernumerary phenotype of Sulf1Δ1

Additional Comments
Genetic Interactions
Statement
Reference

In dlpMH20 Sulf1Δ1 double mutants the number of ectopic mechanosensory bristles is increased.

Embryos mutant for both zygotic and maternal dlpMH20 and dallyMH32 (dlpMH20, dallyMH32) exhibit a denticle phenotype stronger than seen in dallyMH32 mutants and exhibit mid-ventral denticle whorls.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of dlpScer\UAS.T:wg,T:Avic\GFP under the control of Scer\GAL4ptc-559.1 significantly rescues the reduction of the vein 3-4 intervein space that is seen in the wings of dlpMH20 escapers.

Expression of dlpScer\UAS.T:Avic\GFP,T:Rnor\CD2 under the control of Scer\GAL4ptc-559.1 does not rescue the reduction of the vein 3-4 intervein space that is seen in the wings of dlpMH20 escapers.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
References (9)