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General Information
Symbol
Dmel\DJ-1αUAS.cYa
Species
D. melanogaster
Name
FlyBase ID
FBal0191186
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-DJ-1A
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of DJ-1α coding sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

DJ-1αdsRNA.Scer\UAS (under the control of Scer\GAL4elav-C155) flies are more sensitive to 3-AT (a known inhibitor of catalase, which converts H2O2 to H20) exposure compared to control flies.

Overexpression of DJ-1αScer\UAS.cYa ubiquitously, under the control of Scer\GAL4da.G32 leads to resistance against H2O2 stress and 3-AT treatment (a known inhibitor of catalase, which converts H2O2 to H20).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of a DJ-1αScer\UAS.cYa transgene partially rescues the DJ-1αdsRNA.Scer\UAS (Scer\GAL4GMR.PF) eye degeneration phenotype.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
DJ-1αScer\UAS.cYa
DJ-1αUAS.cYa
Name Synonyms
Secondary FlyBase IDs
    References (3)