FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ir75aMB00253
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General Information
Symbol
Dmel\Ir75aMB00253
Species
D. melanogaster
Name
FlyBase ID
FBal0192843
Feature type
allele
Associated gene
Dmel\Ir75a
Associated Insertion(s)
Mi{ET1}Ir75aMB00253
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
    Nature of the Allele
    Allele class

    amorphic allele - molecular evidence

    (Prieto-Godino et al., 2016)
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Mi{ET1}Ir75aMB00253
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    Mi{ET1}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        In olfactory preference assays for polyamines, Ir75aMB00253/Ir75aMB00253 flies do not show any significant difference in their attraction to putrescine or cadaverine, as compared to wild type.

        (Hussain et al., 2016)

        Ir75aMB00253/Df(3L)BSC415 ac2 sensilla have significantly reduced responses to acetic acid and propionic acid, but not to pyridine or 1,4-diaminobutane, compared to controls.

        (Prieto-Godino et al., 2016)

        Sound-evoked compound action potentials in the antennal nerve are not significantly different from wild type in mutant flies. However, nonlinear mechanical amplification is significantly reduced compared to wild type.

        (Senthilan et al., 2012)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        CG14585MB00253
        (Bellen, 2006.10.16)
        IR75aMB00253
        (Hussain et al., 2016)
        Ir75aMB00253
        (Prieto-Godino et al., 2016, Senthilan et al., 2012)
        Name Synonyms
        Secondary FlyBase IDs
          References (4)