FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\exNY1
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General Information
Symbol
Dmel\exNY1
Species
D. melanogaster
Name
FlyBase ID
FBal0193399
Feature type
allele
Associated gene
Dmel\ex
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Tyler et al., 2007)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous clones induced in the eye occupy most of the eye and cause overgrowth.

      (Tyler et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      exNY1 is a recessive, cell-autonomous mutation that allows recovery of Df(1)su(s)R194/+ clones in the adult eye in animals with mosaic eyes containing two genotypes of cells with respect to RpL36; cells which are Df(1)su(s)R194/+ and cells in which the haplo-insufficiency of Df(1)su(s)R194/+ for RpL36 has been rescued by RpL36+t4 (in a wild-type background the Df(1)su(s)R194/+ clones are eliminated by cell competition and are not seen in the adult eye in these animals). Mosaic wing discs contain a similar number of apoptotic cells compared to control discs. The apoptotic cells are predominantly of the Df(1)su(s)R194/+ ; exNY1 genotype and adjacent to the clone boundary.

      Df(1)su(s)R194/+ ; exNY1 Mad10 clones are recovered in adult eyes, although they are smaller than Df(1)su(s)R194/+ ; exNY1 clones.

      (Tyler et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      ex1

      (Tyler et al., 2007)

      exe1

      (Tyler et al., 2007)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: A mutation that allows survival of cells being competed due to haplo-insufficiency for RpL36.

      (Tyler et al., 2007)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      2L-19
      (Tyler et al., 2007)
      exNY1
      (Anderson et al., 2017, Tyler et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)