FB2026_02 , released June 18, 2026
Allele: Dmel\kuk+t8.2
Open Close
General Information
Symbol
Dmel\kuk+t8.2
Species
D. melanogaster
Name
FlyBase ID
FBal0193452
Feature type
allele
Associated gene
Dmel\kuk
Associated Insertion(s)
Carried in Construct
P{kuk+t8.2}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Brandt, 2006)
wild_type
(Brandt, 2006)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Brandt, 2006)
wild_type
(Brandt, 2006)
Mutagen
in vitro construct
(Brandt, 2006, Brandt et al., 2006)
Progenitor genotype
Carried in construct
P{kuk+t8.2}
Cytology
Description

8.2kb EcoRV-EcoRV fragment containing kuk.

(Brandt, 2006)
Allele components
Component
Use(s)
Regulatory region(s)
kuk
Encoded product / tool
kuk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:17,077,235..17,085,503 [+]
Linked to:
EcoRV-EcoRV restriction fragment
Comment:

Position of rescue fragment on reference sequence inferred by FlyBase curator.

(Brandt, 2006)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos from transgenic flies with six copies of kuk+t.8.2kb exhibit very ruffled and abnormally shaped nuclei.

      (Brandt et al., 2006)

      Flies with 6xkuk+t.8.2kb exhibit reduced viability and fertility (20% hatching rate).

      The nuclear-morphology phenotype of kukEY07696 is complemented by a maternal copy of kuk+t.8.2kb but not by a zygotic wild-type allele.

      Flies carrying 6 copies of kuk+t8.2 exhibit reduced viability and fertility (20% hatching rate).

      (Brandt, 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      kuk+t8.2 rescues kukEY07696

      (Brandt, 2006)
      Comments

      The nuclear-morphology phenotype of kukEY07696 is complemented by a maternal copy of kuk+t8.2.

      (Brandt, 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      kuk+t.8.2kb
      kuk+t8.2
      Name Synonyms
      Genomic rescue construct of Brandt
      Secondary FlyBase IDs
        References (2)