FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\meltUAS.cTa
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General Information
Symbol
Dmel\meltUAS.cTa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Teleman
FlyBase ID
FBal0193838
Feature type
allele
Associated gene
Dmel\melt
Associated Insertion(s)
Carried in Construct
P{UAS-melt.T}
Also Known As
UAS-melt
Key Links
Transgenic product class
cDNA
(Teleman et al., 2005)
wild_type
(Teleman et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Teleman et al., 2005)
wild_type
(Teleman et al., 2005)
Mutagen
in vitro construct
(Teleman et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-melt.T}
Cytology
Description

Expression of full length melt cDNA is under the control of UASt sequences.

(Teleman et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
melt
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4en.PU>meltScer\UAS.cTa adult wings are slightly larger than control wings expressing only the driver.

      Strong overexpression meltScer\UAS.cTa in the developing and adult eye does not noticeably affect eye size or morphology.

      (Jukam et al., 2013)

      The total number of photoreceptors, as well as the number of Rh5-positive and Rh6-positive photoreceptors is normal in the eyes of larvae expressing meltScer\UAS.cTa under the control of Scer\GAL4so-7.GAL4.

      (Sprecher et al., 2007)

      Expression of meltScer\UAS.cTa in all photoreceptors, driven by Scer\GAL4GMR.long, causes R8 photoreceptors to adopt a p fate. The dorsal rim area R8 cells are not affected. Expression of meltScer\UAS.cTa, under the control of Scer\GAL4Rh5.PT and Scer\GAL4Rh6.PD in R8 photoreceptor cells, increases the number of cells that adopt an R8 fate and causes ~63% of cells to express both Rh5 and Rh6, which are indicative of both p and y fates. Expression of this transgene in R7 photoreceptor cells, driven by Scer\GAL4Rh3.PP and Scer\GAL4Rh4.PT, does not affect the fate specification of R8 cells.

      (Mikeladze-Dvali et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Eyes that express meltScer\UAS.cTa, under the control of Scer\GAL4GMR.long, in a sev14 background, have a high proportion of pR8 photoreceptors and a small proportion of yR8 receptors.

      (Mikeladze-Dvali et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      meltUAS.cTa/Scer\GAL4αTub84B.PL rescues Df(3L)meltΔ1

      (Teleman et al., 2005)
      Comments

      The growth defects seen in Df(3L)meltΔ1 homozygous flies are fully rescued by meltScer\UAS.cTa with Scer\GAL4αTub84B.PL or Scer\GAL4ppl.PP, but not with Scer\GAL4Ilp3.PC.

      (Teleman et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      meltScer\UAS.cTa
      meltUAS.cTa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Teleman
      Secondary FlyBase IDs
        References (7)