FlyBase Allele Report: Dmel\spn-E[100.37]

General Information

Symbol

Dmel\spn-E^100.37

Species

D. melanogaster

Name

FlyBase ID

FBal0194090

Feature type

allele

Associated gene

Dmel\spn-E

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Nucleotide substitution: G488A.

(Ott et al., 2014)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3R:15,840,814..15,840,814 [+]

Nucleotide change:

G15840814C

Amino acid change:

G487A | spn-E-PA

Reported amino acid change:

G488A

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Ott et al., 2014)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

dorsal appendage (with spn-E^hls-Δ125)

(Ott et al., 2014)

egg (with spn-E^hls-Δ125)

(Ott et al., 2014)

Detailed Description

Statement

Reference

The eggs laid by spn-E^100.37/spn-E^hls-Δ125 mutant females exhibit moderate dorsoventral patterning defects. The majority of eggs laid are collapsed but many eggs with fused or no dorsal appendages are also seen.

(Ott et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

R. Lehmann

(Vagin et al., 2006)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

spn-E^100-37

(Ott et al., 2014)

spn-E^100.37

(Teixeira et al., 2017, Nagao et al., 2010)

spnE^100.37

(Vagin et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

Open Close