FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Myo31DFUAS.GFP
Open Close
General Information
Symbol
Dmel\Myo31DFUAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0194495
Feature type
allele
Associated gene
Dmel\Myo31DF
Associated Insertion(s)
Carried in Construct
P{UAS-Myo31DF.GFP}
Also Known As
UAS-Myo31DF-GFP, UAS-Myo1D-GFP
Key Links
Transgenic product class
wild_type
(Speder et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Speder et al., 2006)
Mutagen
in vitro construct
(Hozumi et al., 2006, Speder et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-Myo31DF.GFP}
Cytology
Description

UASt regulatory sequences drive expression of the full length Myo31DF coding region tagged with GFP.

(Speder et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Myo31DF
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Males expressing Myo31DFScer\UAS.T:Avic\GFP under the control of Scer\GAL4Myo31DF-NP1548 show normal male genital rotation.

      (Petzoldt et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Myo31DFScer\UAS.T:Avic\GFP suppresses the defects in male genital rotation caused by expression of Myo61FScer\UAS.T:Disc\RFP under the control of Scer\GAL4Myo31DF-NP1548, such that all males show normal dextral rotation of the genitalia.

      (Petzoldt et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4ptc-559.1/Myo31DFUAS.GFP rescues Myo31DFL152/Myo31DFK2

      (Okumura et al., 2015)

      Scer\GAL4ptc-559.1/Myo31DFUAS.GFP rescues Myo31DFK1

      (Speder et al., 2006)
      Partially rescues

      Myo31DFUAS.GFP, Scer\GAL4byn-Gal4, Scer\GAL80ts.αTub84B partially rescues Myo31DFL152

      (Hozumi et al., 2008)

      Myo31DFUAS.GFP/Scer\GAL4Abd-B-LDN partially rescues Myo31DFK1

      (Speder et al., 2006)
      Comments

      Expression of Myo31DFScer\UAS.T:Avic\GFP under the control of Scer\GAL4ptc-559.1 completely rescues the change in direction of male genitalia rotation seen in Myo31DFK2/Myo31DFL152 mutant pupae. Mutants expressing Myo31DFScer\UAS.T:Avic\GFP undergo the 360[o] dextral (right-handed) rotation rather than the left-handed (sinistral) rotation seen in Myo31DFK2/Myo31DFL152 mutations.

      (Okumura et al., 2015)

      Expression of Myo31DFScer\UAS.T:Avic\GFP in embryos raised at 18[o]C under the control of Scer\GAL4byn-Gal4 and Scer\GAL80ts.αTub84B partially rescues the left-right (LR) inversion of the gut seen in Myo31DFL152 mutants. Approximately 45% of embryos show gut inversion, compared to 40% in the absence of the driver. When embryos undergo a 60 minute temperature shift to 32[o]C at between 10 and 12.75 hours after egg laying effectively rescued the LR defects, The efficiency of rescue increasing up to 12 hours after egg laying but if the temperature shift takes place after 13 hours after egg laying rescue is less effective. The embryos shifted to 32[o]C at 12.75 hours are mostly at the late stage of germband retraction.

      (Hozumi et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Myo31DFGFP
      (Taniguchi et al., 2011)
      Myo31DFScer\UAS.T:Avic\GFP
      Myo31DFUAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (13)