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General Information
Symbol
Dmel\DebclGS2263
Species
D. melanogaster
Name
FlyBase ID
FBal0194704
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{GSV1}DebclGS2263
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of debclGS2263, under the control of Scer\GAL4elav-C155, extends lifespan slightly (78.3 days vs. 72.3 days in controls).

Ectopic expression of debclGS2263 at moderate levels, under the control of Scer\GAL4GMR.PF, causes no detectable phenotype in the eye.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Ectopic expression of debclGS2263, under the control of Scer\GAL4GMR.PF, suppresses the Hsap\MJDQ78.Scer\UAS.T:Ivir\HA1-induced neurodegeneration of the eye. In addition, debclGS2263 markedly rescues the early adult death of flies expressing Hsap\MJDQ78.Scer\UAS.T:Ivir\HA1 in their neurons, driven by Scer\GAL4elav-C155.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
DebclGS2263
debclGS2263
Name Synonyms
Secondary FlyBase IDs
    References (1)