FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\IKKεGS11377
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General Information
Symbol
Dmel\IKKεGS11377
Species
D. melanogaster
Name
FlyBase ID
FBal0194829
Feature type
allele
Associated gene
Dmel\IKKε
Associated Insertion(s)
P{GSV6}IKKεGS11377
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GSV6}IKKεGS11377
    Cytology
    Description

    The insertion can induce Scer\GAL4-mediated transcription of ik2.

    (Kanuka et al., 2005)
    Allele components
    Component
    Use(s)
    Inserted element
    P{GSV6}
    Regulatory region(s)
    UASt
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mild overexpression of ik2GS11377 under the control of Scer\GAL4neur-P72 (using the temperature sensitive Scer\GAL80ts.αTub84B allele to overcome early lethality) results in thin, tapered bristles.

        (Otani et al., 2011)

        Expression of ik2GS11377 under the control of Scer\GAL4btl.PS disrupts the epithelia of tracheal tubules in embryos. Apical F actin is dispersed and the lumenal structure is not visible but there is no increase in cell death.

        (Oshima et al., 2006)

        Expression using Scer\GAL4Rh3.PP results in several ommatidia lacking R7 neurons at 10 days of age.

        (Kanuka et al., 2005)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        IKKεGS11377
        (Oshima et al., 2006)
        Ik2GS11377
        (Caussinus et al., 2008)
        ik2GS11377
        Name Synonyms
        Secondary FlyBase IDs
          References (5)