FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\TpiUAS.cCa
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General Information
Symbol
Dmel\TpiUAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Celotto
FlyBase ID
FBal0195206
Feature type
allele
Associated gene
Dmel\Tpi
Associated Insertion(s)
Carried in Construct
P{UAS-Tpi.C}
Key Links
Transgenic product class
wild_type
(Celotto et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Celotto et al., 2006)
Mutagen
in vitro construct
(Celotto et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-Tpi.C}
Cytology
Description

UAS regulatory sequences drive expression of nucleotides 57-1371 of Tpi.

(Celotto et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Tpi
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing TpiScer\UAS.cCa under the control of Scer\GAL4Act5C.PI show a modest but significant decrease in lifespan compared to controls.

      Flies expressing TpiScer\UAS.cCa under the control of Scer\GAL4Act5C.PI do not have a bang sensitive phenotype at either room temperature or at 29[o]C.

      (Seigle et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Act5C.PI/TpiUAS.cCa rescues Tpisgk-1

      (Celotto et al., 2006)
      Partially rescues

      Scer\GAL4Act5C.PI/TpiUAS.cCa partially rescues Tpisgk-1

      (Seigle et al., 2008)
      Comments

      Expression of TpiScer\UAS.cCa under the control of Scer\GAL4Act5C.PI partially rescues the reduced median lifespan of Tpisgk-1 homozygotes.

      (Seigle et al., 2008)

      Expression of TpiScer\UAS.cCa under the control of Scer\GAL4Act5C.PI rescues the stress sensitivity and reduced life span of Tpisgk-1 flies.

      (Celotto et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      TpiScer\UAS.cCa
      TpiUAS.cCa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Celotto
      Secondary FlyBase IDs
        References (2)