FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\brpUAS.GFP
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General Information
Symbol
Dmel\brpUAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0195569
Feature type
allele
Associated gene
Dmel\brp
Associated Insertion(s)
Carried in Construct
P{UAS-brp.GFP}
Also Known As
UAS-Brp-GFP, uas-Brp::GFP, UAS-Brp, UAS-brp:GFP
Key Links
Transgenic product class
cDNA
(Wagh et al., 2006)
wild_type
(Wagh et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wagh et al., 2006)
wild_type
(Wagh et al., 2006)
Mutagen
in vitro construct
(Wagh et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-brp.GFP}
Cytology
Description

UASt regulatory sequences drive expression of the 5'UTR and coding regions of brp, which is tagged with GFP at the N-terminus. The brp coding sequences correspond to cDNA AT09405.

(Wagh et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
brp
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of brpScer\UAS.T:Avic\GFP driven by Scer\GAL4BG380 or Scer\GAL4elav.Switch.PO leads to increased quantal content {QC) at larval neuromuscular junctions.

      (Tsurudome et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Heterozygosity for Df(2R)Exel6285 can suppress the increase in quantal content (QC) associated with Scer\GAL4elav.Switch.PO-driven overexpression of brpScer\UAS.T:Avic\GFP back to wild-type levels.

      There is no statistical difference in quantal content (QC) and evoked excitatory junctional currents (EJCs) between homozygous Df(2R)KT40 mutants and Df(2R)KT40 mutants overexpressing brpScer\UAS.T:Avic\GFP driven by Scer\GAL4BG380.

      (Tsurudome et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      brpScer\UAS.T:Avic\GFP
      brpUAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (19)