FB2025_05 , released December 11, 2025
Allele: Dmel\neurBG02391
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General Information
Symbol
Dmel\neurBG02391
Species
D. melanogaster
Name
FlyBase ID
FBal0195628
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Cytology
    Description

    P{GT1} insertion approximately 70bp upstream of exon 1 of transcripts neur-RA and neur-RB and in the first intron of transcripts neur-RC and neur-RD.

    P{GT1} insertion in intron 1.

    Allele components
    Component
    Use(s)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Homozygous males and females show a significant reduction in the number of sternopleural bristles compared to controls.

    Homozygous males show a significant reduction in the number of abdominal bristles compared to controls.

    Mutant flies show reduced behavioural avoidance responses to benzaldehyde compared to controls.

    Mutants show normal locomotor activity.

    The average number of aggressive encounters by males competing for a limited food supply after a period of food deprivation is approximately 1.8 fold greater in neurBG02391 males than in controls.

    Gross morphological defects are not seen in the α-lobes of the mushroom body or in the ellipsoid body of neurBG02587 adults. However, detailed morphometric analysis reveals that the width of the α- and β-lobes is significantly increased in neurBG02391 adults compared to controls and that the neurBG02391 animals show a reduction in ellipsoid body surface.

    Mutants show a reduced olfactory avoidance response to 0.03, 0.10 or 0.30% benzaldehyde compared to control flies, while the avoidance response is not significantly from that of control flies at benzaldehyde concentrations of 1.0 or 3.0%.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (2)