FB2026_02 , released June 18, 2026
Allele: Dmel\laza+t10.35
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General Information
Symbol
Dmel\laza+t10.35
Species
D. melanogaster
Name
FlyBase ID
FBal0196202
Feature type
allele
Associated gene
Dmel\laza
Associated Insertion(s)
Carried in Construct
P{laza.10.35}
Also Known As
laza+
Key Links
Transgenic product class
genomic_DNA
(Kwon and Montell, 2006)
wild_type
(Kwon and Montell, 2006)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Kwon and Montell, 2006)
wild_type
(Kwon and Montell, 2006)
Mutagen
in vitro construct
(Kwon and Montell, 2006, Kwon and Montell, 2006)
Progenitor genotype
Carried in construct
P{laza.10.35}
Cytology
Description

10.35kb of the laza locus that includes 6.1kb of 5' and 3.2kb of 3' untranslated region.

(Kwon and Montell, 2006)
Allele components
Component
Use(s)
Regulatory region(s)
laza
Encoded product / tool
laza
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      laza+t10.35 rescues laza1

      (Kwon et al., 2008)

      laza+t10.35 rescues lazaEY04417

      (Kwon and Montell, 2006)

      laza+t10.35 rescues laza1

      (Kwon and Montell, 2006)
      Comments

      The presence of laza+t.10.35kb in laza1 significantly rescues the ability to discriminate between 18 and 24[o]C.

      (Kwon et al., 2008)

      Expression of laza+t.10.35kb in a lazaEY04417 background rescues the phototransduction response.

      Introduction of the laza+t.10.35kb transgene restores the deactivation kinetics of laza1 mutants to wild-type levels.

      (Kwon and Montell, 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      laza+t.10.35kb
      laza+t10.35
      Name Synonyms
      Secondary FlyBase IDs
        References (3)