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FB2026_02
,
released June 18, 2026
LPP
lipid phosphate phosphohydrolase that functions during phototransduction - along with rdgA regulates amplification and response termination during phototransduction
Please see the JBrowse view of Dmel\laza for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\laza using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads.
JBrowse - Visual display of RNA-Seq signals
View Dmel\laza in JBrowse
3-47
3-44.0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Gene expression is increased in response to the presence of either one or two copies of Scer\GAL4hs.PB.
Source for identity of: laza CG11440
Owing to the ability of mutants in this gene to rescue degeneration in blind mutants of the rdgA gene, this gene is named "lazaro" (laza). This name derives from the Spanish novel "Lazarillo de Tormes", in which Lazaro is the boy servant of a blind man and helps him to see.
The gene is referred to as lazaro (laza), as the name is based on the novel Lazarillo de Tormes, in which the orphan boy Lazaro, helps a blind man see.
