FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Pink1+tCa
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General Information
Symbol
Dmel\Pink1+tCa
Species
D. melanogaster
Name
FlyBase ID
FBal0196295
Feature type
allele
Associated gene
Dmel\Pink1
Associated Insertion(s)
Carried in Construct
P{Pink1+tCa}
Key Links
Transgenic product class
genomic_DNA
(Clark et al., 2006)
wild_type
(Clark et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Clark et al., 2006)
wild_type
(Clark et al., 2006)
Mutagen
in vitro construct
(Clark et al., 2006)
Progenitor genotype
Carried in construct
P{Pink1+tCa}
Cytology
Description

A genomic fragment containing the complete Pink1 gene and portions of CG4095 and CG3184.

(Clark et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
Pink1
Encoded product / tool
Pink1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Pink1+tCa rescues Pink15

      (Yun et al., 2008)

      Pink1+tCa rescues Pink1unspecified

      (Clark et al., 2006)

      Pink1+tCa rescues Pink15

      (Clark et al., 2006)

      Pink1+tCa rescues Pink19

      (Clark et al., 2006)
      Comments

      Expression of Pink1+tCa rescues the male sterility, indirect flight muscle degeneration and mitochondrial defects seen in Pink15 mutant flies.

      (Yun et al., 2008)

      Pink1+tCa almost completely suppresses the defects in mitochondrial morphology and individualisation seen during spermatogenesis in Pink1 mutant males. The indirect flight muscle defects seen in Pink1 mutant adults are fully rescued by Pink1+tCa.

      Pink15 and Pink19 males rescued with Pink1+tCa are fertile.

      (Clark et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Pink1+tCa
      Name Synonyms
      Secondary FlyBase IDs
        References (2)