FB2026_02 , released June 18, 2026
Allele: Dmel\Pink1βTub85D.PC
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General Information
Symbol
Dmel\Pink1βTub85D.PC
Species
D. melanogaster
Name
β-Tubulin at 85D promoter construct of Clark
FlyBase ID
FBal0196297
Feature type
allele
Associated gene
Dmel\Pink1
Associated Insertion(s)
Carried in Construct
P{TMR-Pink1.C}
Also Known As
TMR-pink1
Key Links
Transgenic product class
wild_type
(Clark et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Clark et al., 2006)
Mutagen
in vitro construct
(Clark et al., 2006)
Progenitor genotype
Carried in construct
P{TMR-Pink1.C}
Cytology
Description

Part of the regulatory region of βTub85D drives expression of Pink1.

(Clark et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
βTub85D
Encoded product / tool
Pink1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      Pink1βTub85D.PC is a non-suppressor of sterile phenotype of parkΔ21

      (Clark et al., 2006)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Pink1βTub85D.PC rescues Pink15

      (Yun et al., 2008)

      Pink1βTub85D.PC rescues Pink1unspecified

      (Clark et al., 2006)
      Comments

      Expression of Pink1βTub85D.PC rescues the mitochondrial morphology defects in Pink15 mutant spermatids. The spherical "onion stage" nebenkern no longer contain vacuoles and, as in wild type, two mitochondrial derivatives are seen in "leaf blade stage" elongating spermatids.

      (Yun et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Pink1βTub85D.PC
      Name Synonyms
      β-Tubulin at 85D promoter construct of Clark
      Secondary FlyBase IDs
        References (2)