Dendritic severing is strongly inhibited in homozygous ddaC neuron clones at 20 hours after puparium formation (APF), with most proximal dendrites remaining intact at this stage in the mutant cells (proximal dendrites can be seen disconnected from the ddaC soma at 5 hours APF in wild-type animals).

Homozygous mutant γ neuron clones in the mushroom body show normal axon pruning at 18 hours APF and then show normal regeneration of the adult axon and dendrites.

At low temperature and in uncrowded culture conditions, rare escaper ik2^alice adults (<1%) are observed, but they die shortly after eclosion. These escapers often exhibit abnormal bristles, both the interommatidial and the humeral bristles are affected. At high magnification, the actin footprints along the length of the bristle shaft in ik2^alice escaper adult eyes appears less organised than those in wild-type bristles. In wild-type, interommatidial bristles are found at alternating vertices, whereas in ik2^alice mutants these bristles are often duplicated at a single vertex and are misshapen and kinked.

More than 95% of the embryos laid by ik2^alice mutant females do not hatch; however, larval cuticle preparations indicate that the embryos aren't dorsalised. The majority of embryos display a bic-like phenotype, ranging from headless embryos to embryos with a duplicated abdomen in place of the head and thorax. In addition to this anteroposterior patterning defect, a large number of embryos from ik2^alice germ-line clones exhibit expanded ventral cuticular structures.

Embryos from ik2^alice germ-line clones are both ventralised and bicaudal, exhibiting a variable phenotype, with expanded ventral denticle bands and filzkorper (a posterior structure) in both the tail and the anterior of the embryo. Approximately 89% of the embryos produced from ik2^alice mutant females are bicaudal with no apparent dorsoventral abnormalities.

At stage 8-9, ik2^alice mutant egg chambers are indistinguishable from wild-type. At stage 9, a subpopulation of microtubules are disrupted in ik2^alice mutants.

At stage 7, in oocytes dervied from females containing ik2^alice germ-line clones, ectopic sites of actin polymerisation are visible.

IKKepsilon[+]/IKKε^alice is an enhancer of larval multidendritic class IV neuron | pupal stage phenotype of Scer\GAL4^ppk.PG, par-1^HMS00405

IKKepsilon[+]/IKKε^alice is an enhancer of dendrite | pupal stage phenotype of Scer\GAL4^ppk.PG, par-1^HMS00405