FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tudB45
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General Information
Symbol
Dmel\tudB45
Species
D. melanogaster
Name
FlyBase ID
FBal0197258
Feature type
allele
Associated gene
Dmel\tud
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Arkov et al., 2006)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q2148term.

(Arkov et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:21,191,020..21,191,020 [+]
Nucleotide change:

C21191020T

Amino acid change:

Q2148term | tud-PA; Q2145term | tud-PB

Reported amino acid change:

Q2148term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Arkov et al., 2006)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Female offspring of tud1/tudB45 mothers exhibit a significant reduction in the number of cap cells and terminal filament cells in the ovaries, as compared with wild type. The morphology and spatial arrangement of cap cells is similar to that in wild type.

      (Panchal et al., 2017)

      Embryos derived from tudB45 females show normal abdomen formation.

      Embryos derived from tudB45 or tudB42/tudB45 females form no germ cells.

      Polar granules are extremely rare in embryos derived from tudB42 females.

      (Arkov et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Not rescued by

      tudB45 is not rescued by tudΔ1.nanos.Tag:HA

      (Arkov et al., 2006)

      tudB45 is not rescued by tudΔ2.nanos.Tag:HA

      (Arkov et al., 2006)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tudB45
      (Stepanik et al., 2016, Smendziuk et al., 2015, Creed et al., 2010, Arkov et al., 2006)
      tudb45
      (Panchal et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)