FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Myd88RNAi.bcd
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General Information
Symbol
Dmel\Myd88RNAi.bcd
Species
D. melanogaster
Name
FlyBase ID
FBal0197407
Feature type
allele
Associated gene
Dmel\Myd88
Associated Insertion(s)
Carried in Construct
P{Medea.myd88}
P{Medea.myd88-int}
Key Links
Transgenic product class
RNAi_reagent
(Chen et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Chen et al., 2007)
Mutagen
in vitro construct
(Chen et al., 2007)
Progenitor genotype
Carried in construct
P{Medea.myd88}
P{Medea.myd88-int}
Cytology
Description

The bcd promoter drives expression of a transcript encoding two copies of mir-6-1 modified to target the Myd88 5' untranslated region.

(Chen et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
bcd
Encoded product / tool
Myd88
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      In embryos carrying the P{Medea.myd88} construct, zygotic expression of Myd88bnk.PC rescues the maternal effect embryonic lethality caused by Myd88miRNA.bcd.

      In embryos carrying the P{Medea.myd88-int} construct, zygotic expression of Myd88bnk.int rescues the maternal effect embryonic lethality caused by Myd88miRNA.bcd.

      (Chen et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      This construct is expected to produce microRNA targeting the Myd88 gene.

      (Chen et al., 2007)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Myd88RNAi.bcd
      Myd88miRNA.bcd
      Name Synonyms
      Secondary FlyBase IDs
        References (2)