FB2026_02 , released June 18, 2026
Allele: Dmel\DATUAS.cKa
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General Information
Symbol
Dmel\DATUAS.cKa
Species
D. melanogaster
Name
FlyBase ID
FBal0197505
Feature type
allele
Associated gene
Dmel\DAT
Associated Insertion(s)
Carried in Construct
P{UAS-DAT.K}
Also Known As
UAS-DAT
Key Links
Transgenic product class
cDNA
(Kume et al., 2005)
wild_type
(Kume et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Kume et al., 2005)
wild_type
(Kume et al., 2005)
Mutagen
in vitro construct
(Kume et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-DAT.K}
Cytology
Description

UASt regulatory sequences drive expression of DAT cDNA.

(Kume et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
DAT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      DA neurons expressing DATScer\UAS.cKa under the control of Scer\GAL4ple.PF confers some resistance to MPP[+] toxicity.

      (Wiemerslage et al., 2013)

      Over-expression of DATScer\UAS.cKa in either Scer\GAL4ple.PF or Scer\GAL4c346 expressing cells results in increased ethanol-induced hyperactivity.

      (Kong et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4elav-C155/DATUAS.cKa partially rescues DATfmn

      (Kume et al., 2005)
      Comments

      Expression of DATScer\UAS.cKa pan-neuronally, under the control of Scer\GAL4elav-C155 partially rescues the DATfmn phenotype (i.e. they exhibit decreased daily activity and prolonged sleep periods).

      (Kume et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DATScer\UAS.cKa
      DATUAS.cKa
      Name Synonyms
      Secondary FlyBase IDs
        References (4)